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New sport nutrition supplements Noopept, cas number 157115-85-0
Product name: Noopept
Other name: N-phenylacetyl-L-prolylglycine ethyl ester
CAS No.:157115-85-0
MF: C17H22N2O4
Molecular Weight: 318.37
Assay: 98.0~101.0%
Appearance: White or colourless crystalline
Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic remedy. It is derived from the racetam family of drugs and shares similar mechanisms of action, but is, according to studies, 1000 times more potent than the prototypical racetam drug, piracetam. Animal studies have shown noopept to be neuroprotective and enhance memory in various tests. Unusually for a peptide-derived compound, noopept displays both high oral bioavailability and good blood–brain barrier penetration in rats (although a previous study concluded that "GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection" and that administration of Noopept only increases the concentration of endogenous nootropic Cyclo-L-prolylglycine), and human studies have shown promising results, with potential application in the treatment of Alzheimer's disease. It is also an "immunocorrector" in mice.
It has been found to stimulate the expression of NGF and BDNF in rat hippocampus.
A new generation of nootropics? Noopept is a nootropic peptide developed and prescribed in Russia. It is derived from the racetam family of compounds and has a common mechanism of action but is purported to be up to 1000 times more potent than piracetam - being the most popular and most researched nootropic of our generation. MechanismPart of the Ampakine sub-class, the Racetam family of nootropics work in part by binding to glutamate receptors. This augments the neurotransmitter glutamate and enables the more fluent encoding of memory and hence significantly boosts learning capacity. However the Racetam family have only weak to moderate AMPA modulation, and possess many different mechanisms of action. Noopept can lead to:
Increased creativity
Improved mood
Reduced stress
Augmented levels of focus and motivation
Higher levels of verbal acuity (I particularly notice this)
Higher self-esteem (as everything seems easier)
New sport nutrition supplements Noopept, cas number 157115-85-0